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Dbp5 associates with RNA-bound Mex67 and Nab2 and its localization at the nuclear pore complex is sufficient for mRNP export and cell viability

In Saccharomyces cerevisiae, the mRNA export receptor Mex67 is recruited to mature nuclear transcripts to mediate mRNA export through the nuclear pore complex (NPC) to the cytoplasm. Mex67 binds transcripts through adaptor proteins such as the poly(A) binding protein Nab2. When a transcript reaches...

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Publicat a:PLoS Genet
Autors principals: Adams, Rebecca L., Wente, Susan R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553267/
https://ncbi.nlm.nih.gov/pubmed/33002012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009033
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