Metformin elicits antitumour effect by modulation of the gut microbiota and rescues Fusobacterium nucleatum-induced colorectal tumourigenesis

BACKGROUND: The effect of metformin on gut microbiota has been reported, but whether metformin can suppress colorectal cancer (CRC) by affecting gut microbiota composition and rescue F. nucleatum-induced tumourigenicity remains unclear. METHODS: To identify microbiota associated with both CRC occurr...

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Publicat a:EBioMedicine
Autors principals: Huang, Xiaowen, Hong, Xialu, Wang, Jilin, Sun, Tiantian, Yu, TaChung, Yu, Yanan, Fang, Jingyuan, Xiong, Hua
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553239/
https://ncbi.nlm.nih.gov/pubmed/33039709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103037
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