Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters

COVID-19 pandemic is the third zoonotic coronavirus (CoV) outbreak of the century after severe acute respiratory syndrome (SARS) in 2003 and Middle East respiratory syndrome (MERS) since 2012. Treatment options for CoVs are largely lacking. Here, we show that clofazimine, an anti-leprosy drug with a...

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Publicado no:Res Sq
Main Authors: Yuan, Shuofeng, Yin, Xin, Meng, XiangZhi, Chan, Jasper, Ye, Zi-Wei, Riva, Laura, Pache, Lars, Chan, Chris Chun-Yiu, Lai, Pok-Man, Chan, Chris, Poon, Vincent, Matsunaga, Naoko, Pu, Yuan, Yuen, Chun-Kit, Cao, Jianli, Liang, Ronghui, Tang, Kaiming, Sheng, Li, Du, Yushen, Xu, Wan, Sze, Kong-Hung, Zhang, Jinxia, Chu, Hin, Kok, Kin-Hang, To, Kelvin, Jin, Dong-Yan, Sun, Ren, Chanda, Sumit, Yuen, Kwok-Yung
Formato: Artigo
Idioma:Inglês
Publicado em: American Journal Experts 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553155/
https://ncbi.nlm.nih.gov/pubmed/33052331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21203/rs.3.rs-86169/v1
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