Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model

The COVID-19 pandemic progresses unabated in many regions of the world. An effective antiviral against SARS-CoV-2 that could be administered orally for use following high-risk exposure would be of substantial benefit in controlling the COVID-19 pandemic. Herein, we show that MK-4482, an orally admin...

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Vydáno v:Res Sq
Hlavní autoři: Rosenke, Kyle, Hansen, Frederick, Schwarz, Benjamin, Feldmann, Friederike, Haddock, Elaine, Rosenke, Rebecca, Meade-White, Kimberly, Okumura, Atsushi, Leventhal, Shanna, Hawman, David W., Ricotta, Emily, Bosio, Catharine M., Saturday, Greg, Feldmann, Heinz, Jarvis, Michael A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Journal Experts 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553153/
https://ncbi.nlm.nih.gov/pubmed/33052329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21203/rs.3.rs-86289/v1
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