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Bioreactor Parameters for Microcarrier-Based Human MSC Expansion under Xeno-Free Conditions in a Vertical-Wheel System

Human mesenchymal stem/stromal cells (hMSCs) have been investigated and proven to be a well-tolerated, safe therapy for a variety of indications, as shown by over 900 registered hMSC-based clinical trials. To meet the commercial demand for clinical manufacturing of hMSCs, production requires a scale...

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Detalhes bibliográficos
Publicado no:Bioengineering (Basel)
Main Authors: Lembong, Josephine, Kirian, Robert, Takacs, Joseph D., Olsen, Timothy R., Lock, Lye Theng, Rowley, Jon A., Ahsan, Tabassum
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552727/
https://ncbi.nlm.nih.gov/pubmed/32650422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering7030073
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