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Sectoral activation of glia in an inducible mouse model of autosomal dominant retinitis pigmentosa

Retinitis pigmentosa (RP) is a group of blinding disorders caused by diverse mutations, including in rhodopsin (RHO). Effective therapies have yet to be discovered. The I307N Rho mouse is a light-inducible model of autosomal dominant RP. Our purpose was to describe the glial response in this mouse m...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Massengill, Michael T., Ash, Neil F., Young, Brianna M., Ildefonso, Cristhian J., Lewin, Alfred S.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552392/
https://ncbi.nlm.nih.gov/pubmed/33046772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73749-y
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