Unique Epigenetic Programming Distinguishes Regenerative Spermatogonial Stem Cells in the Developing Mouse Testis

Spermatogonial stem cells (SSCs) both self-renew and give rise to progenitors that initiate spermatogenic differentiation in the mammalian testis. Questions remain regarding the extent to which the SSC and progenitor states are functionally distinct. Here we provide the first multiparametric integra...

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Vydáno v:iScience
Hlavní autoři: Cheng, Keren, Chen, I-Chung, Cheng, Ching-Hsun Eric, Mutoji, Kazadi, Hale, Benjamin J., Hermann, Brian P., Geyer, Christopher B., Oatley, Jon M., McCarrey, John R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552105/
https://ncbi.nlm.nih.gov/pubmed/33083754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101596
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