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The Phage-Encoded N-Acetyltransferase Rac Mediates Inactivation of Pseudomonas aeruginosa Transcription by Cleavage of the RNA Polymerase Alpha Subunit

In this study, we describe the biological function of the phage-encoded protein RNA polymerase alpha subunit cleavage protein (Rac), a predicted Gcn5-related acetyltransferase encoded by phiKMV-like viruses. These phages encode a single-subunit RNA polymerase for transcription of their late (structu...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Ceyssens, Pieter-Jan, De Smet, Jeroen, Wagemans, Jeroen, Akulenko, Natalia, Klimuk, Evgeny, Hedge, Subray, Voet, Marleen, Hendrix, Hanne, Paeshuyse, Jan, Landuyt, Bart, Xu, Hua, Blanchard, John, Severinov, Konstantin, Lavigne, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552054/
https://ncbi.nlm.nih.gov/pubmed/32887488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12090976
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