Germ-Free Conditions Modulate Host Purine Metabolism, Exacerbating Adenine-Induced Kidney Damage

Alterations in microbiota are known to affect kidney disease conditions. We have previously shown that germ-free conditions exacerbated adenine-induced kidney damage in mice; however, the mechanism by which this occurs has not been elucidated. To explore this mechanism, we examined the influence of...

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Bibliografiske detaljer
Udgivet i:Toxins (Basel)
Main Authors: Mishima, Eikan, Ichijo, Mariko, Kawabe, Takeshi, Kikuchi, Koichi, Akiyama, Yukako, Toyohara, Takafumi, Suzuki, Takehiro, Suzuki, Chitose, Asao, Atsuko, Ishii, Naoto, Fukuda, Shinji, Abe, Takaaki
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551802/
https://ncbi.nlm.nih.gov/pubmed/32859011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12090547
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