Imipramine Influences Body Distribution of Supplemental Zinc Which May Enhance Antidepressant Action

Zinc (Zn) was found to enhance the antidepressant efficacy of imipramine (IMI) in human depression and animal tests/models of depression. However, the underlying mechanism for this effect remains unknown. We measured the effect of intragastric (p.o.) combined administration of IMI (60 mg/kg) and Zn...

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Bibliografiske detaljer
Udgivet i:Nutrients
Main Authors: Rafało-Ulińska, Anna, Poleszak, Ewa, Szopa, Aleksandra, Serefko, Anna, Rogowska, Magdalena, Sowa, Ireneusz, Wójciak, Magdalena, Muszyńska, Bożena, Krakowska, Agata, Gdula-Argasińska, Joanna, Kała, Katarzyna, Jasiewicz, Barbara, Opoka, Włodzimierz, Szewczyk, Bernadeta, Nowak, Gabriel
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551732/
https://ncbi.nlm.nih.gov/pubmed/32825449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12092529
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