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Binding Sites of Anti-Lcr V Monoclonal Antibodies Are More Critical than the Avidities and Affinities for Passive Protection against Yersinia pestis Infection in a Bubonic Plague Model

Plague is a zoonotic disease that is caused by Yersinia pestis. Monoclonal antibodies (mAbs) that bind to the V-antigen, a virulence factor that is produced by Y. pestis, can passively protect mice from plague. An analysis of protective mAbs that bind to V-antigen was made to assess binding sites, a...

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Detalhes bibliográficos
Publicado no:Antibodies (Basel)
Main Authors: Amemiya, Kei, Dankmeyer, Jennifer L., Keasey, Sarah L., Trevino, Sylvia R., Wormald, Michael M., Halasohoris, Stephanie A., Ribot, Wilson J., Fetterer, David P., Cote, Christopher K., Worsham, Patricia L., Adamovicz, Jeffrey J., Ulrich, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551159/
https://ncbi.nlm.nih.gov/pubmed/32756297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib9030037
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