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SOURCE: a phase 3, multicentre, randomized, double-blind, placebo-controlled, parallel group trial to evaluate the efficacy and safety of tezepelumab in reducing oral corticosteroid use in adults with oral corticosteroid dependent asthma

BACKGROUND: Many patients with severe asthma continue to experience asthma symptoms and exacerbations despite standard-of-care treatment. A substantial proportion of these patients require long-term treatment with oral corticosteroids (OCS), often at high doses, which are associated with considerabl...

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Podrobná bibliografie
Vydáno v:Respir Res
Hlavní autoři: Wechsler, Michael E., Colice, Gene, Griffiths, Janet M., Almqvist, Gun, Skärby, Tor, Piechowiak, Teresa, Kaur, Primal, Bowen, Karin, Hellqvist, Åsa, Mo, May, Garcia Gil, Esther
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550846/
https://ncbi.nlm.nih.gov/pubmed/33050928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-01503-z
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