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The Unfolded Protein Response and Autophagy as Drug Targets in Neuropsychiatric Disorders

Neurons are polarized in structure with a cytoplasmic compartment extending into dendrites and a long axon that terminates at the synapse. The high level of compartmentalization imposes specific challenges for protein quality control in neurons making them vulnerable to disturbances that may lead to...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Srinivasan, Vignesh, Korhonen, Laura, Lindholm, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550790/
https://ncbi.nlm.nih.gov/pubmed/33132844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.554548
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