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The Borealin dimerization domain interacts with Sgo1 to drive Aurora B–mediated spindle assembly

The chromosomal passenger complex (CPC), which includes the kinase Aurora B, is a master regulator of meiotic and mitotic processes that ensure the equal segregation of chromosomes. Sgo1 is thought to play a major role in the recruitment of the CPC to chromosomes, but the molecular mechanism and con...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Bonner, Mary Kate, Haase, Julian, Saunders, Hayden, Gupta, Hindol, Li, Biyun Iris, Kelly, Alexander E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550704/
https://ncbi.nlm.nih.gov/pubmed/32697622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-05-0341
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