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The GPR40 Agonist GW9508 Enhances Neutrophil Function to Aid Bacterial Clearance During E. coli Infections

G-protein-coupled receptor 40 (GPR40) is known to play a role in the regulation of fatty acids, insulin secretion, and inflammation. However, the function of this receptor in human neutrophils, one of the first leukocytes to arrive at the site of infection, remains to be fully elucidated. In the pre...

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Опубликовано в: :Front Immunol
Главные авторы: Souza, Patricia R., Walker, Mary E., Goulding, Nicolas J., Dalli, Jesmond, Perretti, Mauro, Norling, Lucy V.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550532/
https://ncbi.nlm.nih.gov/pubmed/33133087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.573019
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