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Novel variants in women with premature ovarian function decline identified via whole-exome sequencing

PURPOSE: To investigate the potential etiologies of premature ovarian insufficiency (POI) and diminished ovarian reserve (DOR). METHODS: Fourteen women with sporadic POI and 6 women with DOR were enrolled. We used whole-exome sequencing (WES) and bioinformatics analysis to identify variants in a sub...

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Detalhes bibliográficos
Publicado no:J Assist Reprod Genet
Main Authors: Tang, Ruiyi, Yu, Qi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550486/
https://ncbi.nlm.nih.gov/pubmed/32789750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-020-01919-y
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