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Tumor-Secreted GRP78 Promotes the Establishment of a Pre-metastatic Niche in the Liver Microenvironment

The liver is an immunologically tolerant organ and a common site of distant metastasis for various cancers. The expression levels of glucose-regulated protein 78 (GRP78) have been associated with tumor malignancy. Secretory GRP78 (sGRP78) released from tumor cells contributes to the establishment of...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Chen, Lu, Zheng, Hao, Yu, Xiang, Liu, Lei, Li, Heli, Zhu, Huifen, Zhang, Zhihong, Lei, Ping, Shen, Guanxin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550426/
https://ncbi.nlm.nih.gov/pubmed/33133103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.584458
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