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Observation of nucleic acids inside living human cells by in-cell NMR spectroscopy

The intracellular environment is highly crowded with biomacromolecules such as proteins and nucleic acids. Under such conditions, the structural and biophysical features of nucleic acids have been thought to be different from those in vitro. To obtain high-resolution structural information on nuclei...

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Vydáno v:Biophys Physicobiol
Hlavní autoři: Yamaoki, Yudai, Nagata, Takashi, Sakamoto, Tomoki, Katahira, Masato
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society of Japan 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550250/
https://ncbi.nlm.nih.gov/pubmed/33110737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2142/biophysico.BSJ-2020006
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