TMT-based quantitative proteomics analysis reveals the attenuated replication mechanism of Newcastle disease virus caused by nuclear localization signal mutation in viral matrix protein

Nuclear localization of cytoplasmic RNA virus proteins mediated by intrinsic nuclear localization signal (NLS) plays essential roles in successful virus replication. We previously reported that NLS mutation in the matrix (M) protein obviously attenuates the replication and pathogenicity of Newcastle...

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Detalhes bibliográficos
Publicado no:Virulence
Main Authors: Duan, Zhiqiang, Yuan, Chao, Han, Yifan, Zhou, Lei, Zhao, Jiafu, Ruan, Yong, Chen, Jiaqi, Ni, Mengmeng, Ji, Xinqin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549962/
https://ncbi.nlm.nih.gov/pubmed/32420802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2020.1770482
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