Virulent infection of outbred Hartley guinea pigs with recombinant Pichinde virus as a surrogate small animal model for human Lassa fever

Arenaviruses, such as Lassa virus (LASV), can cause severe and fatal hemorrhagic fevers (e.g., Lassa fever, LF) in humans with no vaccines or therapeutics. Research on arenavirus-induced hemorrhagic fevers (AHFs) has been hampered by the highly virulent nature of these viral pathogens, which require...

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Vydáno v:Virulence
Hlavní autoři: Lan, Shuiyun, Shieh, Wun-Ju, Huang, Qinfeng, Zaki, Sherif R., Liang, Yuying, Ly, Hinh
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549944/
https://ncbi.nlm.nih.gov/pubmed/32799623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2020.1809328
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