Insertion and deletion evolution reflects antibiotics selection pressure in a Mycobacterium tuberculosis outbreak

In genome evolution, genetic variants are the source of diversity, which natural selection acts upon. Treatment of human tuberculosis (TB) induces a strong selection pressure for the emergence of antibiotic resistance-conferring variants in the infecting Mycobacterium tuberculosis (MTB) strains. MTB...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Godfroid, Maxime, Dagan, Tal, Merker, Matthias, Kohl, Thomas A., Diel, Roland, Maurer, Florian P., Niemann, Stefan, Kupczok, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549793/
https://ncbi.nlm.nih.gov/pubmed/32997707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008357
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