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Stable tRNA halves can be sorted into extracellular vesicles and delivered to recipient cells in a concentration-dependent manner

Extracellular vesicles (EVs) are cell-derived nanoparticles that act as natural carriers of nucleic acids between cells. They offer advantages as delivery vehicles for therapeutic nucleic acids such as small RNAs. Loading of desired nucleic acids into EVs can be achieved by electroporation or transf...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Gámbaro, Fabiana, Li Calzi, Marco, Fagúndez, Pablo, Costa, Bruno, Greif, Gonzalo, Mallick, Emily, Lyons, Shawn, Ivanov, Pavel, Witwer, Kenneth, Cayota, Alfonso, Tosar, Juan Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549683/
https://ncbi.nlm.nih.gov/pubmed/31885318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1708548
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