The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation

Recent work has associated point mutations in both zinc fingers (ZnF) of the spliceosome component U2AF35 with malignant transformation. However, surprisingly little is known about the functionality of the U2AF35 ZnF domains in general. Here we have analysed key functionalities of the ZnF domains of...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Herdt, Olga, Reich, Stefan, Medenbach, Jan, Timmermann, Bernd, Olofsson, Didrik, Preußner, Marco, Heyd, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549681/
https://ncbi.nlm.nih.gov/pubmed/32116123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2020.1732701
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