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Short hairpin RNA attenuates liver fibrosis by regulating the PPAR-γ and NF-κB pathways in HBV-induced liver fibrosis in mice

Progressive liver fibrosis, caused by chronic viral infection and metabolic disorders, results in the development of cirrhosis and hepatocellular carcinoma. However, no antifibrotic therapies have been approved to date. In our previous study, adeno-associated virus (AAV) short hairpin RNAs (shRNAs)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Oncol
Hauptverfasser: Ye, Lei, Chen, Ting, Cao, Jiaqi, Sun, Liying, Li, Wuping, Zhang, Chenghai
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549542/
https://ncbi.nlm.nih.gov/pubmed/33491741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2020.5125
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