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Handling Missing Values in Interrupted Time Series Analysis of Longitudinal Individual-Level Data

BACKGROUND: In the interrupted time series (ITS) approach, it is common to average the outcome of interest at each time point and then perform a segmented regression (SR) analysis. In this study, we illustrate that such ‘aggregate-level’ analysis is biased when data are missing at random (MAR) and p...

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Detalhes bibliográficos
Publicado no:Clin Epidemiol
Main Authors: Bazo-Alvarez, Juan Carlos, Morris, Tim P, Pham, Tra My, Carpenter, James R, Petersen, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549500/
https://ncbi.nlm.nih.gov/pubmed/33116899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CLEP.S266428
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