Adherent cell depletion promotes the expansion of renal cell carcinoma infiltrating T cells with optimal characteristics for adoptive transfer

BACKGROUND: Tumor-infiltrating lymphocyte (TIL) therapy is a personalized cancer treatment which involves generating ex vivo cultures of tumor-reactive T cells from surgically resected tumors and administering the expanded TILs as a therapeutic infusion. Phase 1 of many TIL production protocols use...

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Detalles Bibliográficos
Publicado en:J Immunother Cancer
Main Authors: Braun, Mitchell W, Abdelhakim, Haitham, Li, Meizhang, Hyter, Stephen, Pessetto, Ziyan, Koestler, Devin C, Pathak, Harsh B, Dunavin, Neil, Godwin, Andrew K
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2020
Assuntos:
Immune Cell Therapies and Immune Cell Engineering
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549459/
https://ncbi.nlm.nih.gov/pubmed/33037114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000706
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