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An Integrated Strategy for Identifying Targets of Ubiquitin-Mediated Degradation in CD4+ T Cells

Ubiquitination is a crucial component of many immune processes. While ubiquitin-mediated degradation is essential to T cell activation via T cell receptor signaling, the specific E3 ligases and substrates involved are not well-understood. Here, we describe a strategy integrating RNA, protein, and po...

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Bibliographic Details
Published in:Methods Mol Biol
Main Authors: Field, Natania S, O’Leary, Claire E, Dybas, Joseph M, Ding, Hua, Oliver, Paula M
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549384/
https://ncbi.nlm.nih.gov/pubmed/31933212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-0716-0266-9_19
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