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AT101-Loaded Cubosomes as an Alternative for Improved Glioblastoma Therapy

INTRODUCTION: AT101, the R-(-)-enantiomer of the cottonseed-derived polyphenol gossypol, is a promising drug in glioblastoma multiforme (GBM) therapy due to its ability to trigger autophagic cell death but also to facilitate apoptosis in tumor cells. It does have some limitations such as poor solubi...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Flak, Dorota K, Adamski, Vivian, Nowaczyk, Grzegorz, Szutkowski, Kosma, Synowitz, Michael, Jurga, Stefan, Held-Feindt, Janka
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549312/
https://ncbi.nlm.nih.gov/pubmed/33116479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S265061
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