AT101-Loaded Cubosomes as an Alternative for Improved Glioblastoma Therapy

INTRODUCTION: AT101, the R-(-)-enantiomer of the cottonseed-derived polyphenol gossypol, is a promising drug in glioblastoma multiforme (GBM) therapy due to its ability to trigger autophagic cell death but also to facilitate apoptosis in tumor cells. It does have some limitations such as poor solubi...

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Detalles Bibliográficos
Publicado en:Int J Nanomedicine
Main Authors: Flak, Dorota K, Adamski, Vivian, Nowaczyk, Grzegorz, Szutkowski, Kosma, Synowitz, Michael, Jurga, Stefan, Held-Feindt, Janka
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2020
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549312/
https://ncbi.nlm.nih.gov/pubmed/33116479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S265061
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