Lipid Droplets Maintain Energy Homeostasis and Glioblastoma Growth via Autophagic Release of Stored Fatty Acids

Recently, lipid metabolism reprogramming has been further evidenced in malignancies via the observation of large amounts of lipid droplets (LDs) in human tumors, including in glioblastoma (GBM), the most lethal primary brain tumor. However, the role played by LDs in tumor cells remains unknown. Here...

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Foilsithe in:iScience
Main Authors: Wu, Xiaoning, Geng, Feng, Cheng, Xiang, Guo, Qiang, Zhong, Yaogang, Cloughesy, Timothy F., Yong, William H., Chakravarti, Arnab, Guo, Deliang
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549116/
https://ncbi.nlm.nih.gov/pubmed/33083736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101569
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