Annexin A5 is essential for PKCθ translocation during T-cell activation

T-cell activation is a critical part of the adaptive immune system, enabling responses to foreign cells and external stimulus. In this process, T-cell antigen receptor (TCR) activation stimulates translocation of the downstream kinase PKCθ to the membrane, leading to NF-κB activation and thus transc...

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Vydáno v:J Biol Chem
Hlavní autoři: Hu, Zhaoqing, Li, Lin, Zhu, Banghui, Huang, Yi, Wang, Xinran, Lin, Xiaolei, Li, Maoxia, Xu, Peipei, Zhang, Xuerui, Zhang, Jing, Hua, Zichun
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549025/
https://ncbi.nlm.nih.gov/pubmed/32796034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015143
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