Structural and Functional Characterization of a Unique AP Endonuclease From Deinococcus radiodurans

Various endogenous and exogenous agents cause DNA damage, including apurinic/apyrimidinic (AP) sites. Due to their cytotoxic effects, AP sites are usually cleaved by AP endonuclease through the base excision repair (BER) pathway. Deinococcus radiodurans, an extraordinary radiation-resistant bacteriu...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: He, Yuan, Wang, Yiyi, Qin, Chen, Xu, Ying, Cheng, Kaiying, Xu, Hong, Tian, Bing, Zhao, Ye, Wang, Liangyan, Hua, Yuejin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548837/
https://ncbi.nlm.nih.gov/pubmed/33117296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01178
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