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Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys

Methocinnamox (MCAM), a mu opioid receptor antagonist with a long duration of action, attenuates heroin self-administration in rhesus monkeys, suggesting it could be an effective treatment for opioid use disorder (OUD). This study examined effects of acute and repeated MCAM administration on self-ad...

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Bibliographic Details
Published in:Neuropsychopharmacology
Main Authors: Maguire, David R., Gerak, Lisa R., Sanchez, Jesus J., Javors, Martin A., Disney, Alex, Husbands, Stephen M., France, Charles P.
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547678/
https://ncbi.nlm.nih.gov/pubmed/32375158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-0698-8
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