N(6)-methyladenosine-dependent pri-miR-17-92 maturation suppresses PTEN/TMEM127 and promotes sensitivity to everolimus in gastric cancer

N(6)-methyladenosine (m(6)A) is the most common epigenetic RNA modification with essential roles in cancer progression. However, roles of m(6)A and its regulator METTL3 on non-coding RNA in gastric cancer are unknown. In this study, we found elevated levels of m(6)A and METTL3 in gastric cancer. Inc...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Sun, Yiting, Li, Song, Yu, Wenbin, Zhao, Zeyi, Gao, Jing, Chen, Cheng, Wei, Meng, Liu, Teng, Li, Lanbo, Liu, Lian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547657/
https://ncbi.nlm.nih.gov/pubmed/33037176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03049-w
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