Australian funnel-web spiders evolved human-lethal δ-hexatoxins for defense against vertebrate predators

Australian funnel-web spiders are infamous for causing human fatalities, which are induced by venom peptides known as δ-hexatoxins (δ-HXTXs). Humans and other primates did not feature in the prey or predator spectrum during evolution of these spiders, and consequently the primate lethality of δ-HXTX...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Herzig, Volker, Sunagar, Kartik, Wilson, David T. R., Pineda, Sandy S., Israel, Mathilde R., Dutertre, Sebastien, McFarland, Brianna Sollod, Undheim, Eivind A. B., Hodgson, Wayne C., Alewood, Paul F., Lewis, Richard J., Bosmans, Frank, Vetter, Irina, King, Glenn F., Fry, Bryan G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547274/
https://ncbi.nlm.nih.gov/pubmed/32958636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004516117
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