Biomimetic microenvironmental preconditioning enhance neuroprotective properties of human mesenchymal stem cells derived from Wharton's Jelly (WJ-MSCs)

Tuning stem cells microenvironment in vitro may influence their regenerative properties. In this study Wharton's Jelly-derived mesenchymal stem cells (WJ-MSCs) were encapsulated in 3D hydrogels derived from human fibrin (FB) or platelet lysate (PL) and the oxygen level was adjusted to physiolog...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Lech, Wioletta, Sarnowska, Anna, Kuczynska, Zuzanna, Dabrowski, Filip, Figiel-Dabrowska, Anna, Domanska-Janik, Krystyna, Buzanska, Leonora, Zychowicz, Marzena
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547118/
https://ncbi.nlm.nih.gov/pubmed/33037314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74066-0
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