Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk

Mammographic density (MD) phenotypes are strongly associated with breast cancer risk and highly heritable. In this GWAS meta-analysis of 24,192 women, we identify 31 MD loci at P < 5 × 10(−8), tripling the number known to 46. Seventeen identified MD loci also are associated with breast cancer ris...

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Publicado no:Nat Commun
Main Authors: Sieh, Weiva, Rothstein, Joseph H., Klein, Robert J., Alexeeff, Stacey E., Sakoda, Lori C., Jorgenson, Eric, McBride, Russell B., Graff, Rebecca E., McGuire, Valerie, Achacoso, Ninah, Acton, Luana, Liang, Rhea Y., Lipson, Jafi A., Rubin, Daniel L., Yaffe, Martin J., Easton, Douglas F., Schaefer, Catherine, Risch, Neil, Whittemore, Alice S., Habel, Laurel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547012/
https://ncbi.nlm.nih.gov/pubmed/33037222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18883-x
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