Blood-brain barrier–penetrating siRNA nanomedicine for Alzheimer’s disease therapy

Toxic aggregated amyloid-β accumulation is a key pathogenic event in Alzheimer’s disease (AD), which derives from amyloid precursor protein (APP) through sequential cleavage by BACE1 (β-site APP cleavage enzyme 1) and γ-secretase. Small interfering RNAs (siRNAs) show great promise for AD therapy by...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Adv
मुख्य लेखकों: Zhou, Yutong, Zhu, Feiyan, Liu, Yang, Zheng, Meng, Wang, Yibin, Zhang, Dongya, Anraku, Yasutaka, Zou, Yan, Li, Jia, Wu, Haigang, Pang, Xiaobin, Tao, Wei, Shimoni, Olga, Bush, Ashley I., Xue, Xue, Shi, Bingyang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Association for the Advancement of Science 2020
विषय:
Research Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546706/
https://ncbi.nlm.nih.gov/pubmed/33036977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc7031
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन