Overlapping activities of ELAV/Hu family RNA binding proteins specify the extended neuronal 3’ UTR landscape in Drosophila

The tissue-specific deployment of highly extended neural 3’ UTR isoforms, generated by alternative polyadenylation (APA), is a broad and conserved feature of metazoan genomes. However, the factors and mechanisms that control neural APA isoforms are not well-understood. Here, we show that three ELAV/...

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Veröffentlicht in:Mol Cell
Hauptverfasser: Wei, Lu, Lee, Seungjae, Majumdar, Sonali, Zhang, Binglong, Sanfilippo, Piero, Joseph, Brian, Miura, Pedro, Soller, Matthias, Lai, Eric C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546445/
https://ncbi.nlm.nih.gov/pubmed/33007254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.09.007
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