Llwytho...

(2S,6S)- and (2R,6R)-hydroxynorketamine inhibit the induction of NMDA receptor-dependent LTP at hippocampal CA1 synapses in mice

The ketamine metabolite (2R,6R)-hydroxynorketamine has been proposed to have rapid and persistent antidepressant actions in rodents, but its mechanism of action is controversial. We have compared the ability of (R,S)-ketamine with the (2S,6S)- and (2R,6R)-isomers of hydroxynorketamine to affect the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Brain Neurosci Adv
Prif Awduron: Kang, Heather, Park, Pojeong, Han, Muchun, Tidball, Patrick, Georgiou, John, Bortolotto, Zuner A., Lodge, David, Kaang, Bong-Kiun, Collingridge, Graham L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7545754/
https://ncbi.nlm.nih.gov/pubmed/33088919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2398212820957847
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!