Deletion of Mitochondrial Uncoupling Protein 2 Exacerbates Mitochondrial Damage in Mice Subjected to Cerebral Ischemia and Reperfusion Injury under both Normo- and Hyperglycemic Conditions

Deletion of mitochondrial uncoupling protein 2 (UCP2) has been shown to aggravate ischemic damage in the brain. However, the underlying mechanisms are not fully understood. The objective of this study is to explore the impact of homozygous UCP2 deletion (UCP2(-/-)) on mitochondrial fission and fusio...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: He, Maotao, Ma, Yanmei, Wang, Rui, Zhang, Jianzhong, Jing, Li, Li, P. Andy
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7545711/
https://ncbi.nlm.nih.gov/pubmed/33061796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.48204
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