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Most Commonly Mutated Genes in High-Grade Serous Ovarian Carcinoma Are Nonessential for Ovarian Surface Epithelial Stem Cell Transformation

High-grade serous ovarian carcinoma (HGSOC) is the fifth leading cause of cancer-related deaths of women in the United States. Disease-associated mutations have been identified by the Cancer Genome Atlas Research Network. However, aside from mutations in TP53 or the RB1 pathway that are common in HG...

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Dades bibliogràfiques
Publicat a:Cell Rep
Autors principals: Yamulla, Robert Joseph, Nalubola, Shreya, Flesken-Nikitin, Andrea, Nikitin, Alexander Yu, Schimenti, John C.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7545232/
https://ncbi.nlm.nih.gov/pubmed/32877668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108086
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