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Targeted delivery of 5-fluorouracil-1-acetic acid (5-FA) to cancer cells overexpressing epithelial growth factor receptor (EGFR) using virus-like nanoparticles

Chemotherapy is widely used in cancer treatments. However, non-specific distribution of chemotherapeutic agents to healthy tissues and normal cells in the human body always leads to adverse side effects and disappointing therapeutic outcomes. Therefore, the main aim of this study was to develop a ta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gan, Bee Koon, Rullah, Kamal, Yong, Chean Yeah, Ho, Kok Lian, Omar, Abdul Rahman, Alitheen, Noorjahan Banu, Tan, Wen Siang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7545207/
https://ncbi.nlm.nih.gov/pubmed/33033330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73967-4
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