Candida Administration Worsens Cecal Ligation and Puncture-Induced Sepsis in Obese Mice Through Gut Dysbiosis Enhanced Systemic Inflammation, Impact of Pathogen-Associated Molecules From Gut Translocation and Saturated Fatty Acid

Obesity induces gut leakage and elevates serum lipopolysaccharide (LPS), a major cell wall component of Gram-negative bacteria, through gut translocation. Because Candida albicans is prominent in human gut but not in mouse, C. albicans, a source of (1→3)-β-D-glucan (BG) in gut contents, was administ...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Panpetch, Wimonrat, Sawaswong, Vorthon, Chanchaem, Prangwalai, Ondee, Thunnicha, Dang, Cong Phi, Payungporn, Sunchai, Tumwasorn, Somying, Leelahavanichkul, Asada
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7545113/
https://ncbi.nlm.nih.gov/pubmed/33101279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.561652
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