Ribonucleocapsid assembly/packaging signals in the genomes of the coronaviruses SARS-CoV and SARS-CoV-2: detection, comparison and implications for therapeutic targeting

The genomic ssRNA of coronaviruses is packaged within a helical nucleocapsid. Due to transitional symmetry of a helix, weakly specific cooperative interaction between ssRNA and nucleocapsid proteins leads to the natural selection of specific quasi-periodic assembly/packaging signals in the related g...

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Bibliographic Details
Published in:J Biomol Struct Dyn
Main Authors: Chechetkin, Vladimir R., Lobzin, Vasily V.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544952/
https://ncbi.nlm.nih.gov/pubmed/32901577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2020.1815581
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