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Upregulation of Mcl-1S Causes Cell-Cycle Perturbations and DNA Damage Accumulation
As an important regulator of apoptosis, Mcl-1 protein, a member of the Bcl-2 family, represents an attractive target for cancer treatment. The recent development of novel small molecule compounds has allowed Mcl-1-inhibitory therapy to proceed to clinical trials in cancer treatment. However, the pos...
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| Publicado no: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7544834/ https://ncbi.nlm.nih.gov/pubmed/33072738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.543066 |
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