Effect of BDNF Val66Met on hippocampal subfields volumes and compensatory interaction with APOE-ε4 in middle-age cognitively unimpaired individuals from the ALFA study

BACKGROUND: Current evidence supports the involvement of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism, and the ε4 allele of APOE gene in hippocampal-dependent functions. Previous studies on the association of Val66Met with whole hippocampal volume included patients of a variety of...

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Pubblicato in:Brain Struct Funct
Autori principali: Vilor-Tejedor, Natalia, Operto, Grégory, Evans, Tavia E., Falcon, Carles, Crous-Bou, Marta, Minguillón, Carolina, Cacciaglia, Raffaele, Milà-Alomà, Marta, Grau-Rivera, Oriol, Suárez-Calvet, Marc, Garrido-Martín, Diego, Morán, Sebastián, Esteller, Manel, Adams, Hieab H., Molinuevo, José Luis, Guigó, Roderic, Gispert, Juan Domingo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544723/
https://ncbi.nlm.nih.gov/pubmed/32804326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-020-02125-3
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