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DNMT1蛋白通过沉默MEG3基因促进视网膜母细胞瘤增殖

OBJECTIVE: To investigate whether DNMT1 protein induces retinoblastoma proliferation by silencing MEG3 gene. METHODS: Two retinoblastoma cell lines (HXO-RB44 and SO-RB50) and a normal human retinal pigment epithelial (RPE) cell line were transfected with the plasmid pcDNA-DNMT1 or si-DNMT1 for up-re...

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Bibliographic Details
Published in:Nan Fang Yi Ke Da Xue Xue Bao
Format: Artigo
Language:Inglês
Published: 南方医科大学学报编辑部 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544569/
https://ncbi.nlm.nih.gov/pubmed/32990237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2020.09.03
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