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Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to oesophageal adenocarcinoma

Oesophageal adenocarcinoma (OAC) is one of the most common causes of cancer deaths. Barrett’s oesophagus (BO) is the only known precancerous precursor to OAC, but our understanding about the molecular events leading to OAC development is limited. Here, we have integrated gene expression and chromati...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Rogerson, Connor, Ogden, Samuel, Britton, Edward, Ang, Yeng, Sharrocks, Andrew D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544504/
https://ncbi.nlm.nih.gov/pubmed/32880368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57189
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