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Base pairing, structural and functional insights into N(4)-methylcytidine (m(4)C) and N(4),N(4)-dimethylcytidine (m(4)(2)C) modified RNA
The N(4)-methylation of cytidine (m(4)C and m(4)(2)C) in RNA plays important roles in both bacterial and eukaryotic cells. In this work, we synthesized a series of m(4)C and m(4)(2)C modified RNA oligonucleotides, conducted their base pairing and bioactivity studies, and solved three new crystal str...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7544196/ https://ncbi.nlm.nih.gov/pubmed/32941619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa737 |
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