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Are long telomeres better than short? Relative contributions of genetically predicted telomere length to neoplastic and non-neoplastic disease risk and population health burden

BACKGROUND: Mendelian Randomization (MR) studies exploiting single nucleotide polymorphisms (SNPs) predictive of leukocyte telomere length (LTL) have suggested that shorter genetically determined telomere length (gTL) is associated with increased risks of degenerative diseases, including cardiovascu...

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發表在:PLoS One
Main Authors: Protsenko, Ekaterina, Rehkopf, David, Prather, Aric A., Epel, Elissa, Lin, Jue
格式: Artigo
語言:Inglês
出版: Public Library of Science 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544094/
https://ncbi.nlm.nih.gov/pubmed/33031470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240185
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