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Are long telomeres better than short? Relative contributions of genetically predicted telomere length to neoplastic and non-neoplastic disease risk and population health burden

BACKGROUND: Mendelian Randomization (MR) studies exploiting single nucleotide polymorphisms (SNPs) predictive of leukocyte telomere length (LTL) have suggested that shorter genetically determined telomere length (gTL) is associated with increased risks of degenerative diseases, including cardiovascu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Protsenko, Ekaterina, Rehkopf, David, Prather, Aric A., Epel, Elissa, Lin, Jue
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544094/
https://ncbi.nlm.nih.gov/pubmed/33031470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240185
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